Tudofovir 300 Tablet

Tudofovir 300 Tablet

650 INR/Bottle

Product Details:

  • Drug Type Other Types
  • Ingredients Each film coated tablet contains: Tenofovir Disoproxil Fumarate IP 300 mg Colours : Indigo Carmine & Titanium Dioxide. PHARMACOLOGY
  • Physical Form Tablets
  • Function Anti-Viral
  • Recommended For HIV infection Chronic hepatitis B virus (HBV) infection
  • Dosage 1 TABLETS DAILY
  • Dosage Guidelines AS PER DIOCTOR ADVICE
  • Click to View more
X

Tudofovir 300 Tablet Price And Quantity

  • 650 INR/Bottle
  • 1 Bottle

Tudofovir 300 Tablet Product Specifications

  • AS PER DIOCTOR ADVICE
  • Suitable For All
  • Each film coated tablet contains: Tenofovir Disoproxil Fumarate IP 300 mg Colours : Indigo Carmine & Titanium Dioxide. PHARMACOLOGY
  • Tablets
  • Other Types
  • Anti-Viral
  • 1 TABLETS DAILY
  • HIV infection Chronic hepatitis B virus (HBV) infection
  • 30 Boxes

Tudofovir 300 Tablet Trade Information

  • Cash on Delivery (COD) Cash Advance (CA)
  • 500 Bottle Per Day
  • 2 Days
  • Contact us for information regarding our sample policy
  • 1*30
  • Asia
  • All India

Product Description

he pharmacokinetics of tenofovir disoproxil fumarate has been evaluated in healthy volunteers and HIV-1 infected individuals. Tenofovir pharmacokinetics is similar between these populations.

Absorption: Tenofovir disoproxil fumarate is a water soluble diester prodrug of the active ingredient tenofovir. The oral bioavailability of tenofovir from tenofovir disoproxil fumarate in fasted patients is approximately 25%. Following oral administration of a single dose of tenofovir disoproxil fumarate 300 mg to HIV-1 infected patients in the fasted state, maximum serum concentrations (C max ) are achieved in 1.0 0.4 hrs. C max and AUC values are 296 90 ng/mL and 2287 685 nghr/mL, respectively.

The pharmacokinetics of tenofovir are dose proportional over a tenofovir disoproxil fumarate dose range of 75 to 600 mg and are not affected by repeated dosing.

Effects of Food on Oral Absorption: Administration of tenofovir disoproxil fumarate following a high-fat meal (700 to 1000 kcal containing 40 to 50% fat) increases the oral bioavailability, with an increase in tenofovir AUC of approximately 40% and an increase in C max of approximately 14%. However, administration of tenofovir disoproxil fumarate with a light meal did not have a significant effect on the pharmacokinetics of tenofovir when compared to fasted administration of the drug. Food delays the time to tenofovir C max by approximately 1 hour.

Distribution: In vitro binding of tenofovir to human plasma or serum proteins is less than 0.7 and 7.2%, respectively, over the tenofovir concentration range 0.01 to 25 g/mL. The volume of distribution at steady state is 1.3 0.6 L/kg and 1.2 0.4 L/kg, following intravenous administration of tenofovir 1.0 mg/kg and 3.0 mg/kg.

Metabolism and Elimination: In vitro studies indicate that neither tenofovir disoproxil nor tenofovir are substrates of CYP450 enzymes.

Following IV administration of tenofovir, approximately 70-80% of the dose is recovered in the urine as unchanged tenofovir within 72 hours of dosing. Following single dose, oral administration of tenofovir disoproxil fumarate, the terminal elimination half-life of tenofovir is approximately 17 hours. After multiple oral doses of tenofovir disoproxil fumarate 300 mg once daily (under fed conditions), 32 10% of the administered dose is recovered in urine over 24 hours.

Tenofovir is eliminated by a combination of glomerular filtration and active tubular secretion.

INDICATIONS TUDOFOVIR is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection.


Enter Buying Requirement Details
Email Id
Mobile number

Other Products in 'Tenofovir Tablets' category



Back to top
trade india member
PHARMA BROTHERS All Rights Reserved.(Terms of Use)
Developed and Managed by Infocom Network Private Limited.